Budesonide (Pulmicort Flexhaler®)
Inhaled Corticosteroid

• Maintenance treatment of asthma and as prophylactic therapy.
        1 to 2  inhalations twice daily for patients who have previously been on bronchodilators alone or inhaled steroids.
        2 to 4 inhalations twice daily for patients who have previously been on oral steroids.
  

(90 mcg/inhalation ,180 mcg/inhalation )


 

Cromolyn (Intal® )
Acts by inhibiting the release of mediators from mast cells.

• Maintenance treatment of asthma and as prophylactic therapy.
       2 inhalations every 6 hours.
• Prevention of acute bronchospasm which follows exercise, exposure to cold dry air or environmental agents:
       2 inhalations 15 minutes before exposure to the precipitating factor.

(800 mcg/inhalation; 112 inhalations per 8.1 g inhaler, 200 inhalations per 14.2 g inhaler )

 

Epinephrine 1:1,000 (Adrenalin ®)
Systemic alpha , beta-1, and beta-2 receptor agonist.
 

• Treatment of acute asthma exacerbations
  
       0.3 to  0.5 mg SQ every 20 minutes for 3 doses.
  

(1 mg/mL ; 1 and 2 mL ampules )
 

Fluticasone (Flovent® HFA):
Inhaled Corticosteroid

• Maintenance treatment of asthma and as prophylactic therapy.
       Initial dose 88 micrograms twice daily for patients previously on bronchodilators alone.
            To maximum dose 440mcg twice daily
       Initial dose 88 to 220 micrograms twice daily for patients previously on cortocosteroids.  
            To maximum dose 440mcg twice daily
       Initial dose 880 micrograms twice daily for patients previously on oral steroids.
  

(44,  110 , or 220  mcg/inhalation MDI; (120 inhalations per canister)

Fluticasone with Salmeterol (Advair Diskus®):
Combination Inhaled Corticosteroid with long acting β₂ agonist bronchodilator.

• Maintenance treatment of asthma and as prophylactic therapy.
  
       1 inhalation twice daily (all strengths)
  
  "Salmeterol, a component of Advair Diskus, may be associated with rare serious asthma episodes or asthma-related deaths. Data are not adequate to determine whether concurrent use of inhaled corticosteroids such as fluticasone proprionate, a component of ADVAIR DISKUS, provides protection from this risk."
  

(100/50, 250/50, or 500/50 mcg containing 100, 250, or 500 mcg of fluticasone propionate, respectively, and 50 mcg of salmeterol per inhalation dry powder inhaler (DPI). 60 blisters per DPI.
 

Ipratropium (Atrovent ®)
Inhaled anticholinergic

• Treatment of acute asthma exacerbations
  
       2 puffs 4 times daily . Not to exceed 12 puffs in 24 hours.
  

18 mcg ipratropium per inhalation; 200 inhalations per 14.7 gram canister)
 

Ipratropium with Albuterol (Combivent ®)
Combination inhaled anticholinergic and β₂ agonist bronchodilator<

• Treatment of acute asthma exacerbations
  
       2 puffs 4 times daily . Not to exceed 12 puffs in 24 hours.
  

(18 mcg ipratropium and 90 mcg of albuterol per inhalation; 200 inhalations per canister)
 

Levalbuterol (R-albuterol)(Xopenex HFAand solution ®)
Inhaled short acting β₂ agonist bronchodilator.

• Treatment of acute asthma exacerbations
  
      1 to 2 puffs every 4 to 6 hours metered dose inhaler (MDI) OR
      Initially 0.63 mg by nebulization 3 times daily. May increase to 1.25mg three times daily. 
   

(45 mcg/ puff; 200 doses per 15 g inhaler; 0.31mg/ 3 mL, 0.63 mg/ 3 ml, 1.25 mg / 3 mL Solution)
 

Methylprednisolone (Medrol®)
Systemic Corticosteoroid.Anti-inflammatory.

• Maintenance treatment of asthma 
  7.5 to 60 mg daily in a single dose in A.M. or QOD as needed for control.
• Treatment of acute asthma exacerbations
  120 to 180 mg / day in in 3 or 4 divided doses for 48 hours, then 60 to 80 mg / day until PEF reaches 70% of predicted personal best.
• Short-course "burst" to achieve control:
  40- 60 mg per day as single dose or 2 divided doses for 3 to 10 days .
  

(2, 4, 8, 16 ,32 mg tablets)
 

Methylprednisolone (Solu-Medrol®)
Systemic Corticosteoroid. Anti-inflammatory.

• Treatment of acute epsiodes of asthma 
  0.5 to 2 mg per kg IV bolus every 6 hours to a maximum of 125 mg per day.

Montelukast (Singulair®):
Leukotriene Receptor Antagonist

• Maintenance treatment of asthma and allergic rhinitis.
  
       10 mg PO daily.
  

(10 mg tablets , 4 or 5 mg chewable tablets, 4 mg oral granules)

 

Prednisone (Deltasone®):
Systemic Corticosteroid

• Maintenance treatment of asthma 
  7.5 to 60 mg daily in a single dose in A.M. or QOD as needed for control.
• Treatment of acute asthma exacerbations
  120 to 180 mg / day in 3 or 4 divided doses for 48 hours, then 60 to 80 mg / day until PEF reaches 70% of predicted personal best.
• Short-course "burst" to achieve control:
  40 to  60 mg per day as single dose or 2 divided doses for 3 to 10 days .
  

(1 , 2.5 , 5, 10, 20 ,50  mg tablets , 5mg/ml, 5mg/5mL)

 

Prednisolone (Delta-Cortef®):
Systemic Corticosteroid

• Maintenance treatment of asthma 
  7.5 to 60 mg daily in a single dose in A.M. or QOD as needed for control.
• Treatment of acute asthma exacerbations
  120 to 180 mg / day in 3 or 4 divided doses for 48 hours, then 60 to 80 mg / day until PEF reaches 70% of predicted personal best.
• Short-course "burst" to achieve control:
  40 to 60 mg per day as single dose or 2 divided doses for 3 to 10 days .
  

(5 mg tablets , 5mg/5 mL solution, 15mg/5mL solution)

 

Terbutaline(Brethine®)
Systemic β₂ agonist bronchodilator.

• Treatment of acute asthma exacerbations
  
       0.25 mg SC every 15 to 30 minutes up to a total dose of 0.5 mg in 4 hours.
  

(1 mg / mL ampules)
 

Theophylline sustained release (Theophylline ER)
Methylxanthine bronchodi lator

• Maintenance treatment of asthma
  
       Starting dose 10 mg/kg/day up to 300 mg maximum dose to reach serum concentrations of 8-12 ug/mL.
  

(100, 200,300,600 mg tablets, 125, 200, 300 mg capsules)
 

Triamcinolone (Azmacort®)
Inhaled Corticosteroid

• Maintenance treatment of asthma and as prophylactic therapy.
       2 puffs TID to QID or 4 puffs BID.
       Up to 16 inhalations per day for very severe asthma .
  

(100  mcg/puffs MDI; (240 puffs per inhaler)

Zafirlukast (Accolate®):
Leukotriene Receptor Antagonist

• Maintenance treatment of asthma and allergic rhinitis.
  
       20 mg PO twice daily
  

(10 and 20 mg tablets)