|
Drug |
Therapeutic range |
Toxic range |
|
Carbamazepine
|
4
- 12 mcg/mL |
greater than 20 mcg/mL
|
|
Digoxin |
0.8 - 2.0
ng/mL |
greater than 2.5 ng/mL |
|
Ethosuximide
|
40
-
100 mcg/mL
|
greater than150 mcg
/mL |
Gentamicin
peak
(standard every 8 hour dosing) |
8 - 10 mcg/mL |
greater than
10 mcg/mL |
Gentamicin
trough
(standard every 8 hour dosing) |
less than 2 -
4 mcg/mL |
greater than
4 mcg/mL |
|
Magnesium |
4.3 - 7.3 mg/dl
(3.5 - 6 mEq/L) |
greater than 8.5 mg/dl
(7 mEq/L) |
|
Phenobarbital
|
15
- 40 mcg/mL
|
greater than 60 mcg/mL |
|
Phenytoin
|
10
- 20 mcg/mL
|
greater than 20 mcg/mL |
|
Procainamide |
4 -
10 mcg/mL |
greater than 10 mcg/mL |
|
Quinidine
|
2 - 5 mcg/mL |
greater than 6 mcg/mL
|
|
Theophylline
|
8 - 20 mcg/mL |
greater than 20 mcg/mL |
|
Valproic acid |
50 -1 00 mcg/mL |
greater than 100 mcg/mL |
|
Vancomycin |
5 - 10 mcg/mL |
greater than 60 mcg/mL |
REFERENCES
1. Tegretol® package insert,
2003.
2. Lanoxin ® package insert,
2005.
3. Dilantin ® package insert,
2003.
4.
Lu JF, Nightingale CH.Magnesium sulfate in eclampsia and pre-eclampsia: pharmacokinetic principles.Clin
Pharmacokinet.2000;38(4):305-14.PMID: 10803454
5. Elin RJ (2004) Reference Intervals and Laboratory Values . In L Goldman, D
Ausiello, eds., Cecil Textbook of Medicine, 22nd ed., vol. 1, pp. 2503.
Philadelphia: Saunders. |
