Some causes of increased CA-125 include nonmucinous epithelial ovarian
carcinoma, Fallopian tumors, cervical adenocarcinoma,
endometrial carcinoma, trophoblastic tumor, carcinomas of the GI tract and lung,
ascites, renal failure, cirrhosis, pancreatitis, benign gastrointestinal diseases,
adenomyosis, uterine fibroids, and pelvic inflammatory disease.
References:
1. .Touitou Y , et. al. Tumour
marker antigens during menses and pregnancy. Br J Cancer. 1989;60:419-20. PMID:2789952
2. Tan MCB, Goedegebuure PS, Eberlein, TJ : Tumor Biology and Tumor Markers
In: Townsend CM Jr, ed. Sabiston Textbook of surgery 18th ed WB Saunders,
Philadelphia, 2007 . p762
3.
Wallach, J. Interpretation
of Diagnostic Tests, Eighth ed. Lippincott Williams & Wilkins, 2007