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Reference Values During Pregnancy


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Ceruloplasmin  (serum)

   Units Nonpregnant Adult First Trimester Second Trimester Third Trimester
mg/dL 25 - 63 30 - 49 40 - 53 43 - 78
mg/L 250 - 630 300 - 490 400 - 530 430 - 780

Some causes of elevated ceruloplasmin include carcinomas, leukemias, Hodgkin disease, primary biliary cirrhosis, lupus , rheumatoid arthritis, pregnancy, exposure to estrogens, and copper intoxication
.
Some causes of decreased ceruloplasmin levels include Wilson disease , Menkes kinky hair syndrome, nephrotic syndromes, malabsorption, and some cases of advanced liver disease


References:

Abbassi-Ghanavati M, Greer LG, Cunningham FG. Pregnancy and laboratory studies: a reference table for clinicians. Obstet Gynecol. 2009 Dec;114(6):1326-31. PMID:19935037
Wallach, J. Interpretation of Diagnostic Tests, Eighth ed. Lippincott Williams & Wilkins, 2007 Fischbach FT, Dunning MB III, eds. A Manual of Laboratory and Diagnostic Tests, 7th ed. Philadelphia, Lippincott Williams and Wilkins,2004

 

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