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Reference Values During Pregnancy


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Complement, C3  (serum)

   Units Nonpregnant Adult First Trimester Second Trimester Third Trimester
mg/dL 83 - 177 44 - 116 58 - 118 60 - 126
g/L 0.83 - 1.77 0.44 - 1.16 0.58 - 1.18 0.6 - 1.26

Some causes of decreased C3 include systemic lupus erythematosus, lupus nephritis, acute poststreptococcal GN,  hereditary deficiency, infancy, massive tissue injury sepsis, and viremia.

Some causes of increased C3 include biliary obstruction, nephrotic syndrome, corticosteroid therapy , and inflammation.
 


References:

1. Lockitch G. Handbook of Diagnostic Biochemistry and Hematology in Normal Pregnancy. Boca Raton:CRC, 1993.
2. Abbassi-Ghanavati M, Greer LG, Cunningham FG. Pregnancy and laboratory studies: a reference table for clinicians. Obstet Gynecol. 2009 Dec;114(6):1326-31. PMID:19935037
3. Wallach, J. Interpretation of Diagnostic Tests, Eighth ed. Lippincott Williams & Wilkins, 2007
 

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