Reference Values For D-dimer in Pregnancy

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Reference Values During Pregnancy

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D-dimer (plasma)

Units	Nonpregnant Adult	First Trimester	Second Trimester	Third Trimester
ľg/mL	< 0.5	0.05 - 0.95	0.32 - 1.29	0.13 -1.7
ľg/L ng/mL	< 500	50 - 950	320 - 1290	130 - 1700
nmol/L	< 2.7	0.3 - 5.2	1.8 - 7.1	0.7 - 9.3

Some causes of an elevated D-dimer include deep vein thrombosis (DVT), pulmonary embolism (PE), disseminated intravascular coagulation (DIC), cancer, underlying inflammation, and cardiac, renal or liver disease .

References:

1. Abbassi-Ghanavati M, Greer LG, Cunningham FG. Pregnancy and laboratory studies: a reference table for clinicians. Obstet Gynecol. 2009 Dec;114(6):1326-31. PMID:19935037
2. Kratz A, Ferraro M, Sluss PM, Lewandrowski KB. Laboratory reference values. N Engl J Med. 2004;351(15):1548-15632. PMID:15470219
3. Wallach, J. Interpretation of Diagnostic Tests, Eighth ed. Lippincott Williams & Wilkins, 2007