X-Linked recessive trait
XXX syndrome ( Triple X syndrome, trisomy X)
A condition characterized by the presence
of three X chromosomes in each of a female's cells, instead of the usual
two X chromosomes. Although females with triple X tend to be slightly taller than
average the effect of having an extra X chromosome appears to be otherwise quite
variable. Many females will show no or few symptoms while others may have
decreased fertility, learning difficulties, and developmental delay and/or behavioral
problems.
XXX syndrome occurs in one out of 1000 female births, and appears to be the
result of an extra X chromosome contributed by the mother's ovum (egg). The
error occurs during the production of the mother's eggs when the X chromosomes
fail to separate and migrate into separate cells. This error in the
distribution of chromosomes during the formation of reproductive cells is called nondisjunction
and occurs more frequently in older mothers.
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Normal
Normal separation and migration of the X chromosome into separate ova
(eggs) |
Nondisjunction
Failure of X chromosomes to detach
and migrate into separate ova (eggs). |