Insulin Adjustment During Antenatal Steroid Treatment with Betamethasone

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Insulin Adjustment During Antenatal Steroid Treatment with
Betamethasone

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Hyperglycemia may be expected to occur as early as 3 to 8 hours after antenatal steroids have been given. Glucose values may remain elevated for up to 5 days after the first dose in diabetic patients. The algorithm developed by Mathiesen ER is used by the calculator below to adjust the insulin dose for the first five days after steroids have been given. The algorithm assumes the first dose of steroid is given in the AM of Day 1 .

Enter insulin doses the day before glucocorticoid treatment

REFERENCES

1. Kalra S, Kalra B, Gupta Y. Glycemic management after antenatal corticosteroid therapy. N Am J Med Sci. 2014 Feb;6(2):71–76. PMID:24696828
2. Star J Hogan J, Sosa ME, Carpenter MW. Glucocorticoid–associated maternal hyperglycemia: A randomized trial of insulin prophylaxis. J Matern Fetal Med. 2000 Sep–Oct;9(5):273–277. PMID: 11132581. PMID:11132581
3. Mathiesen ER, et. al., Insulin dose during glucocorticoid treatment for fetal lung maturation in diabetic pregnancy: test of an algorithm [correction of analgoritm]. Acta Obstet Gynecol Scand. 2002 Sep;81(9):835-9.PMID:12225298

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