Should a pregnant NICU nurse receive the Tdap (pertussis) vaccine?
The California Department of Public Health (CDPH) recommends Tdap vaccination for:
- Anyone 7 years and older who is not fully immunized
- Women of childbearing age — including before, during, or after pregnancy
- People who have close contact with pregnant women or infants
The CDC Advisory Committee on Immunization Practices (ACIP) states that Tdap may be given during pregnancy when a woman is at increased risk for pertussis exposure — such as health-care personnel, including NICU nurses, or women living or working where a pertussis outbreak is occurring. Administration in the second or third trimester is preferred.
Pregnant patients should be informed of:
- the limited pregnancy-specific safety data for Tdap
- the uncertain degree of infant protection via maternal antibodies
- the theoretical possibility that maternal antibodies could modify infant responses to DTaP or conjugate vaccines containing diphtheria or tetanus toxoid
Vaccination of pregnant women with Tdap should be reported to the corresponding manufacturer’s pregnancy registry:
- ADACEL®: Sanofi Pasteur — 1-800-822-2463
- BOOSTRIX®: GlaxoSmithKline — 1-888-825-5249
SEE ALSO: Vaccines
References ▼
1. California Department of Public Health. CDPH broadens recommendations for vaccinating against pertussis.
Accessed 8/29/2010.
http://www.cdph.ca.gov/Pages/PH10-048.aspx
2. Murphy TV, et al. Prevention of pertussis, tetanus, and diphtheria among pregnant and postpartum women and their infants. MMWR Recomm Rep. 2008;57(RR-4):1–51. PMID:18509304
2. Murphy TV, et al. Prevention of pertussis, tetanus, and diphtheria among pregnant and postpartum women and their infants. MMWR Recomm Rep. 2008;57(RR-4):1–51. PMID:18509304