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Midtrimester Risk for Chromosome Abnormalities

Midtrimester Risk of Anomaly Based on Maternal Age

years
REFERENCES:
California Prenatal Screening Program Handbook 2023
https://www.cdph.ca.gov/Programs/CFH/DGDS/CDPH%20Document%20Library/PNS%20Documents/Provider_Handbook_Appendix_D.pdf
ACCESSED 4/6/2023

1. Morris JK et al. Revised estimates of the maternal age specific live birth prevalence of Down Syndrome, J Med 2002; 9:2–6.
2. Hook, K.B. Chromosome abnormalities and spontaneous fetal deaths following amniocentesis; further data and associations with maternal age. Am J Hum Genet 1983; 35:110–116.
3. Hook, B.B., Cross, P.K., Schreinemachers, D.M. Chromosomal abnormality rates at amniocentesis and live‐born infants. J Am Med Assoc 1983; 249:2034–2038.

SEE ALSO: Risk of Chromosome Abnormality at Term

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